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Sunday, May 25, 2014

Detection of Glyphosate Residues in Animals and Humans

"In the present study glyphosate residues were tested in urine and different organs of dairy cows as well as in urine of hares, rabbits and humans using ELISA and Gas Chromatography-Mass Spectroscopy (GC-MS). The correlation coefficients between ELISA and GC-MS were 0.96, 0.87, 0.97and 0.96 for cattle, human, and rabbit urine and organs, respectively. The recovery rate of glyphosate in spiked meat using ELISA was 91%. Glyphosate excretion in German dairy cows was significantly lower than Danish cows. Cows kept in genetically modified free area had significantly lower glyphosate concentrations in urine than conventional husbandry cows.

Also glyphosate was detected in different organs of slaughtered cows as intestine, liver, muscles, spleen and kidney. Fattening rabbits showed significantly higher glyphosate residues in urine than hares. Moreover, glyphosate was significantly higher in urine of humans with conventional feeding. Furthermore, chronically ill humans showed significantly higher glyphosate residues in urine than healthy population. The presence of glyphosate residues in both humans and animals could haul the entire population towards numerous health hazards, studying the impact of glyphosate residues on health is warranted and the global regulations for the use of glyphosate may have to be re-evaluated.......



Introduction 
Glyphosate (N-phosphonomethyl glycine) is registered as herbicide for many food and non-food crops as well as non-crop areas where total vegetation control is desired. The predominating uses of glyphosate, in descending order, are stubble management, pre-sowing application and pre-harvest application (desiccation). Glyphosate is also used to prevent weeds in fields with glyphosate resistant genetically modified (GM) crops like soybean, rapeseed, corn, etc. Since 1996 the amount and the number of genetically engineered crops dramatically increased worldwide. It is estimated that 90% of the transgenic crops grown worldwide are glyphosate resistant .

The rapidly growing problem of glyphosate-resistant weeds is reflected in steady increases in the use of glyphosate on crops. Steams, leaves and beans of glyphosate resistant soy are contaminated with glyphosate. Moreover, due to the intensive use of glyphosate it was frequently detected in water, rain and air. Chang and coworkers detected glyphosate concentrations in air and rain up to 2.5 μg/L in agricultural areas in Mississippi and Iowa. In Europe GM soybean for food and feed was admitted in 1996. All animals and humans eating this soy chronically incorporate unknown amounts of this herbicide.

Residues of glyphosate in tissues and organs of food animals fed with GM feed (soybean, corn, etc.) are not considered or neglected in legislation. The influence of glyphosate residues on the quality of animal Products intended for human food is almost unknown. The incorporation of GM soybean meal in broiler feed significantly affects the color parameter for breast muscles. In contrast Erickson and coworkers  did not find any effects on the performance and carcass characteristics of feedlot steers. Furthermore, glyphosate is a potent chelator fixing trace and macro elements.....